The police have activated Ananda Alerts for 13-year-old Shanel Pinnock and Romario Watson, 16.
Shanel is from Rose Heights, St James and has been missing since Sunday, September 9.
She is of dark complexion, slim build and about five-feet-six inches tall.
The Mount Salem police report that Shanel was last seen at home about 6:00 pm, but has not been seen or heard from since. At the time she went missing she was wearing a black skirt and a black blouse.
Romario is from Ensom City, Spanish Town, St Catherine and has been missing since Thursday September 6.
He is of dark complexion, slim build, about five-feet-eight inches tall with a tattoo on his left hand.
The Spanish Town police report that Romario was last seen at home about 6:00pm, but has not been seen or heard from since. At the time he went missing he was wearing a purple and white, checkered sweater and cut-off black pants.
Anyone knowing the whereabouts of Shanel Pinnock or Romario Watson is being asked to contact the Mount Salem Police at 952-3572, the Spanish Town Police at 984-2305, Police 119 emergency number or the nearest Police Station.