KYIV, Ukraine (AP) — A Russian airstrike devastated a maternity hospital Wednesday in the besieged port city of Mariupol and wounded at least 17 people, Ukrainian officials said, amid growing warnings from the West that Moscow’s invasion is about to take a more brutal and indiscriminate turn.

The ground shook more than a mile away when a series of blasts slammed into the Mariupol complex, blowing out windows and ripping away much of the front of one building. Police and soldiers rushed to scene to evacuate victims, carrying out a heavily pregnant and bleeding woman on a stretcher.

Another woman wailed as she clutched her child. In the courtyard, mangled cars burned, and a blast crater went at least two stories deep.

President Volodymyr Zelenskyy wrote on Twitter that there were “people, children under the wreckage” and called the strike an “atrocity”. Video shared by Zelenskyy showed cheerfully painted hallways strewn with twisted metal.

“There are few things more depraved than targeting the vulnerable and defenseless,” British Prime Minister Boris Johnson tweeted, adding that Russian President Vladimir Putin will be held “to account for his terrible crimes”.

Authorities, meanwhile, announced new ceasefires Wednesday morning to allow thousands of civilians to escape from bombarded towns around Kyiv as well as the southern cities of Mariupol, Enerhodar and Volnovakha, Izyum in the east and Sumy in the northeast.

It was not immediately clear whether anyone was able to leave other cities, but people streamed out of Kyiv’s suburbs, many headed for the city centre, as explosions were heard in the capital and air raid sirens sounded repeatedly.

From there, the evacuees planned to board trains bound for western Ukrainian regions not under attack.

Civilians leaving the Kyiv suburb of Irpin were forced to make their way across the slippery wooden planks of a makeshift bridge, because the Ukrainians blew up the concrete span to Kyiv days ago to slow the Russian advance.

With sporadic gunfire echoing behind them, firefighters dragged an elderly man to safety in a wheelbarrow, a child gripped the hand of a helping soldier, and a woman inched her way along cradling a fluffy cat inside her winter coat. They trudged past a crashed van with the words “Our Ukraine” written in the dust coating its windows.

“We have a short window of time at the moment,” said Yevhen Nyshchuk, a member of Ukraine’s territorial defence forces. “Even if there is a ceasefire right now, there is a high risk of shells falling at any moment.”

Previous attempts to establish safe evacuation corridors over the past few days largely failed because of what the Ukrainians said were Russian attacks. But Putin, in a telephone call with Germany’s chancellor, accused militant Ukrainian nationalists of hampering the evacuations.

In Mariupol, local authorities hurried to bury the dead from the past two weeks of fighting in a mass grave. City workers dug a trench some 25 metres long at one of the city’s old cemeteries and made the sign of the cross as they pushed bodies wrapped in carpets or bags over the edge.

Nationwide, thousands are thought to have been killed, both civilians and soldiers, in the two weeks of fighting since Putin’s forces invaded. The UN estimates more than two million people have fled the country, the biggest exodus of refugees in Europe since the end of World War II.

The fighting knocked out power to the decommissioned Chernobyl nuclear plant, raising fears about the spent fuel that is stored at the site and must be kept cool. But the UN nuclear watchdog agency said it saw “no critical impact on safety” from the loss of power.

The crisis is likely to get worse as Moscow’s forces step up their bombardment of cities in response to what appear to be stronger Ukrainian resistance and heavier Russian losses than anticipated.

Echoing remarks from the director of the CIA a day earlier, British Defence Secretary said Russia’s assault will get “more brutal and more indiscriminate” as Putin tries to regain momentum.

Britain’s Defence Ministry said fighting continued northwest of Kyiv. The cities of Kharkiv, Chernihiv, Sumy and Mariupol were being heavily shelled and remained encircled by Russian forces.

Russian forces are placing military equipment on farms and amid residential buildings in the northern city of Chernihiv, Ukraine’s military said. In the south, Russians in civilian clothes are advancing on the city of Mykolaiv, a Black Sea shipbuilding centre of a half-million people, it said.

The Ukrainian military, meanwhile, is building up defences in cities in the north, south and east, and forces around Kyiv are “holding the line” against the Russian offensive, authorities said.

In Irpin, a town of 60,000, police officers and soldiers helped elderly residents from their homes. One man was hoisted out of a damaged structure on a makeshift stretcher, while another was pushed toward Kyiv in a shopping cart. Fleeing residents said they had been without power and water for the past four days.

Regional administration head Oleksiy Kuleba said the crisis for civilians is deepening in and around Kyiv, with the situation particularly dire in the suburbs.

“Russia is artificially creating a humanitarian crisis in the Kyiv region, frustrating the evacuation of people and continuing shelling and bombing small communities,” he said.

The situation is even worse in Mariupol, a strategic city of 430,000 people on the Sea of Azov that has been encircled by Russian forces for the past week.

Efforts to evacuate residents and deliver badly needed food, water and medicine failed Tuesday because of what the Ukrainians said were continued Russian attacks.

The city took advantage of a lull in the shelling Wednesday to hurriedly bury 70 people. Some were soldiers, but most were civilians.

The work was conducted efficiently and without ceremony. No mourners were present, no families to say their goodbyes.

One woman stood at the gates of the cemetery to ask whether her mother was among those being buried. She was.