Keeping a keen eye south of the border, the Obama administration is intensifying its engagement with Latin America, hosting leaders from a pair of presidents at the White House and sending Vice President Joe Biden to visit two others.

Peru’s President Ollanta Humala and Chile’s President Sebastian Pinera will travel to Washington in June to meet with President Barack Obama, the White House said Wednesday. And next week, Biden will make stops in Brazil and Colombia, plus the Caribbean nation of Trinidad and Tobago.

Dovetailing on Obama’s trip last week to Mexico and Costa Rica, the visits reflect the administration’s desire to show the US relationship with its neighbors to the south is about much more than drugs, crime and illegal immigration. The need for closer economic ties topped Obama’s agenda during the three-day trip.

“All told, we will have the most active stretch of high-level engagement on Latin America in a long, long time,” Biden said Wednesday at the State Department. “There are so many opportunities. There’s so much more we believe we can do.”

Of intense interest to leaders and citizens in Latin American countries is the immigration overhaul advancing tenuously through Congress. Obama is largely supportive of the bipartisan bill, which would strengthen borders and provide a pathway to citizenship for many of the 11 million people in the US illegally — most of them from Latin American countries.

The June 4 visit by the Chilean leader will focus on regional cooperation on education, the economy, energy and the environment, the White House said. A similar roster of topics was set to dominate the session with Peru’s president on June 11.

High on the agenda for both meetings will be negotiations over the Trans-Pacific Partnership, an Asia-Pacific-wide trading bloc meant to open markets to wider trade. Peru and Chile are members, as are Mexico and Canada. The pact is key to Obama’s vaunted strategy to forge closer ties to Asia as China and other regional nations gain economic clout.

Ricardo Zuniga, who heads Latin America policy for the White House’s National Security Council, said the US wants to make sure other countries in the Western Hemisphere aren’t left out of that process.

“The countries in the Americas are more active global players,” Zuniga said. “We’re running into each other in more parts of the world and in more multilateral organizations.”

In Colombia, Biden will meet with President Juan Manuel Santos for a security-focused discussion that will also touch on economic issues. Although Colombia isn’t initially part of the trade partnership with Asia, Zuniga said, the US has been supporting Colombia’s aspirations to join the Organization for Economic Cooperation and Development, or OECD. The US also wants to show it supports peace talks between Colombia’s government and the Revolutionary Armed Forces of Colombia, or FARC, taking place in Cuba.

Brazilian President Dilma Rousseff will host Biden for meetings there focused on the economy, the White House said. In Trinidad and Tobago, an archipelago of the coast of Venezuela, Prime Minister Kamla Persad-Bissessar is inviting leaders from numerous Caribbean countries to talk economic collaboration and security with Biden.