WASHINGTON (AP) — The country’s monkeypox outbreak can still be stopped, US health officials said Thursday, despite rising case numbers and so far limited vaccine supplies.

The Biden administration’s top health official pushed back against criticism about the pace of the response and worries that the US has missed the window to contain the virus, which has been declared a global emergency.

“We believe we have done everything we can at the federal level to work with our state and local partners and communities affected to make sure we can stay ahead of this and end this outbreak,” Xavier Becerra, head of the Department of Health and Human Services, told reporters on a call.

But he added that local health officials “must do their part. … We don’t have the authority to tell them what to do.”

The pushback from federal leaders came as they announced distribution plans for 780,000 shots of the two-dose Jynneos vaccine. The doses will be allocated to states, cities and other localities based on their case numbers and the size of their populations that are considered high-risk for the disease.

Health departments in San Francisco;, New York, Washington, D.C., and elsewhere say they still don’t have enough shots to meet demand and have stopped scheduling appointments for second vaccine doses to stretch supplies.

Becerra said the federal government has done its job and said the onus is now on local officials to use the tools available.

“We’ve made vaccines, tests and treatments well beyond the numbers that are currently needed available to all jurisdictions,” he said.

But one representative for specialty health clinics said Becerra’s comments showed a “lack of understanding for the full breadth of this crisis.”

“Clinics around the country are pleading with federal health officials for the information, supplies and staffing they need to successfully bring an end to this outbreak,” said David C. Harvey, executive director of the National Coalition of STD Directors, in a statement. The group is pressing for $100 million in emergency funding for local health departments and clinics.

There were more than 4,600 reported monkeypox cases in the US as of late Wednesday, according to the CDC, and federal officials expect those numbers to rise.

More than 99 per cent of reported cases are in men and the vast majority of those are among men who reported sexual contact with other men, though health officials have stressed that anyone can catch the virus.

The US is now capable of testing 60,000 to 80,000 people per day, though Becerra said daily testing numbers are well below that.

The monkeypox virus mainly spreads through skin-on-skin contact, but it can also transmit through touching linens used by someone with the infection. People with monkeypox may experience fever, body aches, chills and fatigue. Many in the outbreak have developed sometimes-painful zit-like bumps.