TORONTO, Canada (AFP) — The biggest film festival in North America opened Thursday in Toronto with the international launch of Oscar-winning Japanese animation master Hayao Miyazaki’s likely last movie, as the twin Hollywood strikes drag on.

Organisers of the event, a launch pad for numerous Academy Award-winning films, were finalising a stacked line-up of premieres, red carpet galas, and prestige TV launches featuring work from dozens of countries when Tinseltown’s actors staged a walkout.

But festival CEO Cameron Bailey says the global reach of the programming, and the ability of film-makers and actors to promote independent fare, even amid the strikes, speaks to the “strength of cinema right now”.

“It took some weeks to really figure out the specifics and the details of how you would navigate a strike-affected festival, but it turns out that we’re going to have lots of red carpet talent,” Bailey told AFP.

Among those expected in Canada’s largest city during the 10-day movie extravaganza are A-listers Patricia Arquette, Taika Waititi, Anna Kendrick, and Ethan Hawke, who all moved behind the camera to direct their latest films.

French film-maker Ladj Ly will debut Les Indesirables, a follow-up look at marginalised communities in the suburbs of Paris four years after his Oscar-nominated debut feature Les Miserables.

Also on tap is the international premiere of awards hopeful The Holdovers from director Alexander Payne (Sideways) about a teacher (Paul Giamatti) tasked with supervising students at a boarding school who cannot go home for Christmas break.

And pop star Lil Nas X will bring some flair to the red carpet for the opening of his documentary Lil Nas X: Long Live Montero — just one of several music films on tap including a world premiere of In Restless Dreams: The Music of Paul Simon.

But the first marquee screening is The Boy and the Heron, Miyazaki’s first feature-length film in a decade — and likely his last for the storied Studio Ghibli, at age 82.

The semi-autobiographical film, which opened in Japan in July, follows young Mahito as he navigates the horrors of World War II and his mother’s death. After meeting a talking heron, he enters a colourful fantasy world in search of her.

“That’s one that we’re especially thrilled to have. This is one of the greatest artists in cinema with what may be his final film,” Bailey said.

“It’s magnificent.”

Also premiering on Thursday night was Arquette’s Gonzo Girl and another directorial debut, North Star from Kristin Scott Thomas.

The Toronto film fest is a key part of the fall festival line-up, along with Venice and Telluride, at which movies hoping to build early Oscars momentum typically hold premieres.

TIFF’s annual People’s Choice Award has become an increasingly accurate Oscars bellwether, predicting eventual best picture winners such as Nomadland and Green Book.

Premiering on Friday will be Dumb Money, starring Seth Rogen and Paul Dano, about the amateur investors who turned GameStop into a Wall Street phenomenon in 2021.

On Saturday, Robert De Niro stars in actor Tony Goldwyn’s Ezra, about a man (Bobby Cannavale) who moves back in with his father (De Niro) after blowing up his career and marriage.

Other world premieres include Waititi’s sports comedy Next Goal Wins and Michael Keaton’s Knox Goes Away, starring Al Pacino.

The festival comes as Hollywood actors and writers strike in a battle with studios and streamers over pay and other work conditions; meaning that union members generally cannot promote films produced by companies involved in the dispute.

Waivers have been offered in some cases, while in others, the films screening in Toronto are not subject to the strikes because they were independently or internationally produced.

TIFF only returned to full strength in 2022, after two years of online or hybrid events staged amid the coronavirus pandemic.

The festival runs until September 17.