DUBAI, United Arab Emirates (AP) — Commercial ships came under attack Sunday by drones and missiles in the Red Sea and a United States (US) warship there opened fire in self-defense as part of an hours-long assault claimed by Yemen’s Houthi rebels, officials said.

The attack potentially marked a major escalation in a series of maritime attacks in the Mideast linked to the Israel-Hamas war as multiple vessels found themselves in the crosshairs of a single Houthi assault for the first time in the conflict.

“We’re aware of reports regarding attacks on the USS Carney and commercial vessels in the Red Sea and will provide information as it becomes available,” the Defense Department told The Associated Press.

The Carney is an Arleigh Burke-class guided-missile destroyer that’s already shot down multiple rockets the Houthis have fired toward Israel so far in the war. It wasn’t damaged in the attack and no injuries were reported on board, said a US official who spoke on condition of anonymity to discuss early details of a military operation.

The Carney responded after hearing from the Bahamas-flagged bulk carrier Unity Explorer that it was under attack by missile fire, the official said. The Carney shot down two drones during the attack, one in self-defense and another after checking on the Unity Explorer, the official said.

Assessments were still being made on the Unity Explorer.

The British military earlier said there had been a suspected drone attack and explosions in the Red Sea, without elaborating.

The Defense Department did not identify where it believed the fire came from. However, Houthi military spokesman Brig. Gen. Yahya Saree claimed the attacks, saying the first vessel was hit by a missile and the second by a drone while in the Bab el-Mandeb Strait that links the Red Sea to the Gulf of Aden.

Saree did not mention any US warship being involved in the attack.

“The Yemeni armed forces continue to prevent Israeli ships from navigating the Red Sea (and Gulf of Aden) until the Israeli aggression against our steadfast brothers in the Gaza Strip stops,” Saree said. “The Yemeni armed forces renew their warning to all Israeli ships or those associated with Israelis that they will become a legitimate target if they violate what is stated in this statement.”

Saree also identified the first vessel as the Unity Explorer, which is owned by a British firm that includes Dan David Ungar, who lives in Israel, as one of its officers. The second was a Panamanian-flagged container ship called Number 9, which is linked to Bernhard Schulte Shipmanagement. Managers for the two vessels could not be immediately reached for comment.

Israeli media identified Ungar as being the son of Israeli shipping billionaire Abraham “Rami” Ungar.