LONDON, United Kingdom (AFP) — Manchester City capitalised on Sadio Mane’s controversial red card to thrash title-rivals Liverpool 5-0, while Manchester United lost their 100 per cent record after a 2-2 draw at Stoke yesterday.

City goalkeeper Ederson was stretchered off in a neck brace after being caught in the face by Mane’s boot as he raced out to head the ball away, with the Liverpool winger dismissed for the clash late in the first half at Eastlands.

City already led 1-0 through Sergio Aguero’s opener at that point and braces from Gabriel Jesus and substitute Leroy Sane completed City’s biggest win over Liverpool since 1937.

City are unbeaten in 12 Premier League games, their best run under Guardiola, while Argentina striker Aguero is now the outright, leading non-European goalscorer in Premier League history with 124 goals.

After a blistering start to the season, United conceded for the first time in the league this term when Eric Maxim Choupo-Moting swept home from Mame Biram Diouf’s 43rd-minute cross to notch his first Stoke goal.

Jose Mourinho’s side drew level at the bet365 Stadium as Henrikh Mkhitaryan’s corner in first-half stoppage time was headed goalwards by Paul Pogba, before deflecting into the net off Marcus Rashford.

The visitors moved ahead in the 57th minute when Mkhitaryan’s defence-splitting pass was converted by Romelu Lukaku after the Belgian forward’s initial effort was saved by Jack Butland.

But when United defender Phil Jones stumbled at a Stoke corner, Cameroon forward Choupo-Moting was unmarked to head the equaliser in the 63rd minute.

At the Emirates Stadium, Arsenal eased the pressure on Arsene Wenger with a vital 3-0 win against Bournemouth.

Subjected to stinging criticism following Arsenal’s damaging defeats against Stoke and Liverpool, it took just six minutes for Danny Welbeck to lift Wenger’s gloom as the Arsenal striker headed home from Sead Kolasinac’s cross.

France forward Alexandre Lacazette doubled Arsenal’s lead in the 27th minute, bagging his second goal since his preseason move from Lyon with a curling strike from the edge of the area.

Welbeck’s second goal, from Aaron Ramsey’s 50th-minute pass, secured Arsenal’s first win since the opening weekend.

Alexis Sanchez came off the bench in the closing stages for his first Arsenal appearance this season, following the collapse of his mooted move to Manchester City on transfer deadline day.

Harry Kane reached his Tottenham century as the England striker’s brace inspired an impressive 3-0 win at Everton.

Kane bagged his 100th Tottenham goal — and first this season — in the 28th minute, looping a long-range cross-shot over Everton goalkeeper Jordan Pickford.

Chelsea survived a tense finish as the champions made it three successive wins with a 2-1 success at Leicester.

Antonio Conte’s side took the lead through Alvaro Morata’s third goal for Chelsea, as the Spain striker peeled away from Wes Morgan to meet Cesar Azpilicueta’s cross with a bullet header in the 41st minute.

N’Golo Kante was a key member of Leicester’s title-winning team two years ago and the Chelsea midfielder returned to haunt his old club with a 50th-minute long-range strike.

Jamie Vardy got one back for Leicester with a penalty.

Brighton secured their first top flight win for 34 years, with Pascal Gross’s double clinching a 3-1 win over West Bromwich Albion at Amex Stadium.

Watford handed Southampton manager Mauricio Pellegrino his first league defeat, 2-0 at St Mary’s.